L12. Neurovascular Friction

The Bimodal Nature of Neurovascular Coupling

Neurons, by virtue of their complex and continuously changing signaling roles in brain, must be able to regulate access to energy in order to maintain their ability to communicate meaningful frequency-encoded information. This is accomplished by release of neurotransmitters to astrocytes that in turn signal the vascular system to increase cerebral blood flow (CBF). This process has been termed ...

Neurovascular Imaging

but also well-controlled manipulations (Allegra Mascaro et al., 2010; Kleinfeld et al., 2011) crucial for testing causality rather than simply establishing a correlation between measurement parameters (that does not automatically imply that one of the parameters drives the other). Moreover, the present collection of papers reaches well beyond the current state of knowledge, defining important q...

Friction Models and Friction Compensation

Friction occurs in all mechanical systems,e.g. bearings, transmissions, hydraulic and pneumatic cylinders, valves, brakes and wheels. Friction appears at the physical interface between two surfaces in contact. Lubricants such as grease or oil are often used but the there may also be a dry contact between the surfaces. Friction is strongly influenced by contaminations. There is a wide range of p...

Stroke and neurovascular protection.

Platelets and neurovascular inflammation.

Platelets participate in haemostasis and in thrombus formation in health and disease. Moreover, they contribute to inflammation and cooperate with immune cells in a magnitude of inflammatory/immune responses. Although the inflammatory response has been recognised to be critical in neuronal diseases such as Alzheimer's disease or multiple sclerosis and its mouse counterpart, experimental autoimm...